How Was LSD Discovered?
LSD was discovered in 1938 because of scientific exploration by Albert Hofmann at Sandoz Pharmaceuticals in Switzerland whiles searching for clinical uses for ergot.
Researchers at the Rockefeller Institute in New York had extracted a synthetic compound found in the ergot organism and named it lysergic acid.
A youthful scientist at Sandoz Laboratory named Albert Hofmann started working with lysergic substances. He was attempting to build a medication for human respiratory and circulatory issues.
In 1938 Hofmann synthesize lysergic acid diethylamide and gave it the lab name LSD-25 since it was the twenty-fifth compound he had created in his arranged trials with Sandoz. (The abbreviation LSD originates from the medication's German name, Lysergsäure-diethylamid)
Sandoz analysts tried LSD-25 first in animal and decided that the medication posed little promise for clinical use.
Albert Hofmann then stopped his examination however got back to the substance five years later, in 1943.
The First LSD Trip.
Determined to continuing his examinations of the substance, Albert Hofmann re-synthesized LSD on April 16th, 1943. On this date Albert Hofmann had the first LSD trip in the world when he had absorbed the substance through the skin on his fingertips during the synesthesia, a short time later Hofmann started to feel a strong feeling of anxiousness and a lighty dazed sensation he chose to return home to rest.
In his 1980 book LSD: My Problem Child, Hofmann talks about his experience in more detail:
"At home I lay down and sank into a not unpleasant intoxicated-like condition, characterized by an extremely stimulated imagination. In a dreamlike state, with eyes closed (I found the daylight to be unpleasantly glaring), I perceived an uninterrupted stream of fantastic pictures, extraordinary shapes with intense, kaleidoscopic play of colors. After some two hours this condition faded away. This was, altogether, a remarkable experience—both in its sudden onset and its extraordinary course. It seemed to have resulted from some external toxic influence" - Albert Hofmann
Hofmann accepted this experience and was fascinated by the substance, three days later on the 19th of April 1943 he deliberately took another dose of LSD.
Hofmann took just 0.25 milligrams (250uq) of the substance, which is small considering the doses required for most traditional medications to have an impact.
He again encountered an assortment of unordinary encounters, some sickening and others lovely. The experience affirmed to Hofmann that LSD-25 was a very powerful substance and left him truly amazed.
The 19th of April 1943 has since been known in the psychedelic community as "Bicycle Day", as Albert Hofmann had started to feel the impacts of the drug as he rode home on a bicycle.
Bicycle Day is widely celebrated each year and only 1 day before 4/20.